People with Crohn's disease and related joint inflammation linked to immune system dysfunction have distinct gut bacteria or microbiota, with the bacterium Mediterraneibacter gnavus being a potential ...

Agomab’s ALK5 inhibitor has proven its ability to target the correct part of the intestine in a phase 2 trial of ...

Upadacitinib induction therapy provides steroid-free clinical remission in over 50% of patients with Crohn's disease who do not respond to conventional treatment and has an acceptable safety profile.

Patients with Crohn’s disease and spondyloarthritis have a unique composition of enteric bacteria that may differentiate them ...

Epstein-Barr virus (EBV), best known as the virus behind mono, has been linked to various autoimmune disorders later in life, including lupus, multiple sclerosis, and rheumatoid arthritis. Now, a ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...