San Francisco has dropped three straight, including meek losses to the Packers and Bills by a combined 53 points, to drop to ...

San Francisco 49ers tight end George Kittle told reporters he had "no idea" why he received just two targets during a 35-10 ...

Rather than viewing this team as one of the class organizations of the NFC, we now need to ponder whether injuries, age, and ...

The wife of San Francisco 49ers offensive tackle Trent Williams announced their son, Trenton O'Brien Williams Jr., was ...

A Bills equipment cart awkwardly interrupted an NBC Sports Bay Area live segment after the 49ers' loss in Buffalo.

San Francisco 49ers player Trent Williams and his wife Sondra are mourning the passing of their newborn son, the couple ...

Buffalo Bills running back James Cook looked phenomenal in his team's Week 13 win over the San Francisco 49ers, and his ...

The San Francisco WAG All-Star has fun and looks good in the snow on Sunday night, but she’s ready to burn her creation.

The Buffalo Bills hammered the San Francisco 49ers 35-10 in a snow-filled rout led by Josh Allen’s 4 TDs. Colin Cowherd ...

San Francisco 49ers star running back Christian McCaffrey receives huge injury update following his exit from the game due to ...

With its 35-10 loss at Buffalo on Sunday night, the 49ers have now dropped three straight to sink to 5-7 on the season. The ...

Matthew Berry, Jay Croucher and Connor Rogers dive into the ramifications of star Christian McCaffrey's latest injury, ...