At 12, after the Arquettes relocated to Los Angeles, she made her acting debut in the music video for The Tubes’ “She’s a Beauty,” Alexis told Index magazine in a 1999 interview.

Alexis Arquette died on Sunday, surrounded by friends and family – which is exactly how the transgender icon lived her life. Breaking on the Hollywood scene at a young age, Alexis appeared in ...

Alexis was born Robert Arquette in Los Angeles in 1969, and she was a performer from a young age, appearing in a music video for The Tubes' "She's a Beauty" at age 12 and the occasional other project.

Alexis was born Robert Arquette in Los Angeles in 1969, and she was a performer from a young age, appearing in a music video for The Tubes' "She's a Beauty" at age 12 and the occasional other project.

Alexis died in September 2016 at 47. The actress and activist, whose story was told in 2007’s Alexis Arquette: She’s My Brother, died from cardiac arrest.

Patricia Arquette gave a compelling speech about transgender rights after she won the award for Outstanding Supporting Actress in a Limited Series or Movie for The Act at the 2019 Emmy Awards.

E ditor’s note: Transgender activist and actress Alexis Arquette died Sunday, Sept. 11, 2016, at age 47. This interview with Patricia Arquette was published in The Times in March 2008.

In an interview with Entertainment Tonight, Arquette criticized the awards show for their omission of her sister, transgender actor and activist, Alexis Arquette, in the annual “In Memoriam ...