Elevated serum urate levels are associated with progression of chronic kidney disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the estimated glomerular ...

Allopurinol, a frequently used gout medication, does not appear to drive up the risk for dying among gout patients who also struggle with chronic kidney disease, new research shows. The finding is ...

June 10, 2010 — Allopurinol may slow progression of renal disease in patients with chronic kidney disease (CKD), according to the results of a prospective, randomized trial published online June 10 in ...

Allopurinol treatment is not associated with increased mortality in patients with gout and chronic kidney disease even at 5 years after starting treatment, a study has found. Around 1 in 5 patients ...

ankle gout Researchers studied the comparative efficacy and safety of urate-lowering therapy – allopurinol vs febuxostat – in the treatment of gout. Allopurinol demonstrates noninferiority and ...

An improved understanding of thiopurine metabolism has enabled individualized dosing of these agents in patients with IBD. Ansari et al. describe the use of allopurinol to deliberately manipulate ...

SINCE its clinical introduction in 1964, allopurinol (4-hydroxypyrazolo-[3,4-d]-pyrimidine) has been increasingly used for the treatment of hyperuricemia of gout, 1, 2 many neoplastic diseases and ...