One of the key features in the evolution of more complex organisms is the emergence of allosteric regulation. Allostery is a process by which a protein’s activity can be modulated by binding an ...

Anapleurosis is the filling of the tricarboxylic acid cycle with four-carbon units. The common substrate for both anapleurosis and glucose phosphorylation in bacteria is the terminal glycolytic ...

The membrane protein complex between the sarcoplasmic reticulum Ca 2+ -ATPase (SERCA) and phospholamban (PLN) controls Ca 2+ transport in cardiomyocytes, thereby modulating cardiac contractility.

We explore what allosteric modulators are, their benefits and drawbacks, and which candidates are currently advancing through ...

The photosynthetic systems of green plants have developed a dual function of efficient light collection under low light intensity and photoprotection under intense sunshine to prevent the oxidative ...

Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation ...

Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation ...

A multinational research team led by researchers at Institute of Science Tokyo, RIKEN, and the University of Toronto has ...

Scientists have, for the first time, observed one of the natural mechanisms underlying the regulation of the levels of growth inhibiting hormone in plants. This mechanism had been hitherto seen in ...