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First-in-class molecules dial down inflammation without compromising immunity

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact—a long-sought goal in treating ...
Phys.org

Success in enzyme research: New class of active compounds regulates inflammatory reactions

Inside cells, two important enzymes act like small central regulatory hubs: dipeptidyl peptidase 8 and 9—DPP8/9 for short. Among other things, they regulate inflammatory reactions and influence ...
Medical Xpress

Two first-in-class antibodies can inhibit inflammation in autoimmune diseases

An international research group directed by UMC Utrecht has developed and characterized two first-in-class antibodies that specifically block the high-affinity IgG receptor FcγRI. Their findings open ...

How body clock may shape inflammation, cancer risk and timing of future treatments

Daily life is shaped by the solar day, influencing when we wake up, eat, work and sleep. Inside the body, a similar internal ...
Business Wire

HiFiBiO Therapeutics Receives FDA Clearance of IND Application for HFB200604, a Best-in-Class BTLA Agonist Antibody for the Treatment of Inflammatory and Immunology Diseases

CAMBRIDGE, Mass.--(BUSINESS WIRE)--HiFiBiO Therapeutics, a clinical stage biotechnology company focused on immune modulation, today announced that the U.S. Food and Drug Administration (FDA) has ...