Researchers report that acetazolamide prevented adverse brain changes caused by cocaine withdrawal in mice, suggesting the approved drug could be repurposed to target relapse-related pathways.

Researchers find that a common glaucoma drug, acetazolamide, can reverse brain changes and prevent relapse in opioid use disorder.

An existing drug currently used to treat glaucoma, altitude sickness, and seizures may also have ...

The treatment of drug addiction remains a significant challenge, with cocaine use disorder (CUD) carrying a high rate of relapse and imposing a significant global burden. Over the past few decades, ...

Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...

Long-term abuse of cocaine induces compensatory changes in numerous genes associated with brain function. These compensatory changes lead to the appearance of the classic series of withdrawal symptoms ...

The Department of Justice (DOJ) recently released "Guidelines for Managing Substance Withdrawal in Jails -- A Tool for Local Government Officials, Jail Administrators, Correctional Officers, and ...

It’s not only people addicted to alcohol or drugs who experience significant withdrawal symptoms if they stop using. Antidepressant (AD) withdrawal symptoms are also common, can be severe and ...

An existing drug currently used to treat glaucoma, altitude sickness, and seizures may also have potential for preventing relapse in opioid use ...