The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

A long-overlooked stretch of the human genome appears to play a distinct role in shaping the social and stereotypic ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

A new study identifies PTCHD1-AS as a key non-coding gene that shapes social and repetitive behaviors in autism without affecting cognition.

Human genes that encode proteins often contain non-coding segments known as introns. Removing introns is crucial for the proper expression of genetic information. Understanding how our cells ...

Scientists uncover gene tied to autism's hallmark behaviors A global research team led by The Hospital for Sick Children has identified PTCHD1-AS, a long non-coding RNA gene on the X chromosome, as ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

Plant molecular evolution offers key insights into how coding and regulatory changes shape the diversity of form and function across the plant kingdom. The ...

Osteoarthritis (OA) is the most common age-related joint disorder, affecting more than 500 million people worldwide and representing a leading cause of ...