DNA-dependent protein kinase (DNA-PK), a multicomponent complex including the DNA-PK catalytic subunit and Ku70/80 heterodimer together with DNA, is central to human DNA damage response and repair.
Biologists have used machine learning, a type of AI, to identify 'synthetic extreme' DNA sequences with specifically designed functions in gene activation. They tested 50 million DNA sequences and ...
Synthetic analogues of mitochondrial DNA (mtDNA) have been reported as potent complement system activators. This study investigated the impact of endogenous mtDNA on complement activation. mtDNA and ...
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