DNA synthesis is vital to several processes in biopharmaceutical innovation, including the development of gene therapies, CRISPR gene editing, antisense oligonucleotides and RNA therapies. The need ...

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins - ...

DNA is the raw material of modern medicine yet is the only part of drug development not accessible at the lab bench. DNA synthesis, the first step in most biological workflows including gene synthesis ...

Tunable DNA hairpin springs stretch millions of protein copies under piconewton tension, enabling bulk biochemical discovery of binding partners invisible to single-molecule techniques.

Scientists are increasingly applying artificial intelligence (AI) to biologics discovery, including de novo protein design. However, complex sequence-function relationships and the need for ...

In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps toward folding proteins into their correct three-dimensional structures ...

There’s an old saying about a dollar waiting on a dime. In other words, a monumental endeavor may become stuck at some point if a key preliminary element remains unavailable. The saying could be ...

Genetic medicines such as cell and gene therapies and mRNA vaccines offer extraordinary promise for treating a variety of diseases, including genetic disorders, cancer, and autoimmune diseases. These ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that ...