The Duke Blue Devils have already beaten the North Carolina Tar Heels twice this season, but head coach Jon Scheyer and his crew haven't faced a challenge quite like the one that awaits in Friday's ACC Tournament semifinals.

The first ACC Tournament semifinal features one of the most storied rivalries in college sports as the Duke Blue Devils (29-3, 20-1) take on the Tar Heels of North Carolina (22-12, 15-7). Storylines abound but the largest is Cooper Flagg's availability.

Analyzing Friday’s North Carolina vs. Duke odds and lines, with college basketball expert picks, predictions and best bets.

Sports analyst Stephen A. Smith gives his thoughts on how the Duke basketball team should treat Cooper Flagg's ankle injury.

Duke’s Cooper Flagg, the ACC’s player and rookie of the year, appeared to injure his left ankle Thursday during the top-ranked Blue Devils’ ACC tournament opener in Charlotte. Flagg came down awkwardly on the foot of Georgia Tech’s Baye Ndongo while pulling down a rebound late in the first half.