Appropriate organization of three germ layers—endoderm, mesoderm and ectoderm—during gastrulation is essential for a developing embryo. Mechanistic studies on the morphogenesis of embryos in ...

An undifferentiated cell found in a differentiated tissue that can renew itself and (with limitations) differentiate to yield the specialized cell types of the tissue from which it originated. A ...

In animal development, organogenesis is the process by which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. The germ layers in organogenesis differ by three ...

Not all stem cells possess an equal potential to produce specialized cell types. The sum potential of a cell to give different specialized cell types is called ‘potency’. ESCs possess pluripotency.