Transcription factors (TFs) control specificity and activity of gene transcription, but whether a relationship between these two features exists is unclear. Here we provide evidence for an ...
Temporal encoding of signalling dynamics is not just widespread; it offers a fundamental information-theoretic advantage in cellular communication. Recent advances in channel capacity measurement and ...
A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA—the first step of the process by which an organism's ...
Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like ...
Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.