Salk researchers have identified a new set of molecules that fuel the growth of tumors in pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer. The new research findings ...

University of Toronto (U of T) researchers have found that cancer cells can enhance tumor growth by hijacking enhancer DNA normally used when tissues and organs are formed. The mechanism, called ...

The researchers unravel the exact mechanism of how developmentally active enhancers become repurposed in a tumor context and show the relevance of this repurposing event for cancer. University of ...

A multi-institutional team of researchers led by Case Western Reserve University has identified a pattern of clustered genetic changes that appear to encourage growth of colorectal cancer tumors—a ...

Colon and rectal cancer rate are on the rise, especially in the young. Scientists don't know what lies behind the increase, but knowing more about colorectal cancer will help improve therapeutics for ...

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory.

To examine the changes that promote cancer metastasis, researchers first developed organoids using primary tumor and metastatic cells from a mouse model of PDA. By comparing these mini organs, the ...

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory.

Genetic mutations can increase a person’s cancer risk, but other gene “enhancer” elements may also be responsible for disease progression, according to new research out of Case Western Reserve ...