Nucleotide excision repair (NER) is a highly conserved pathway that recognises and removes bulky lesions and helix‐distorting adducts from DNA, thereby safeguarding genomic integrity. In bacteria, the ...
Base excision repair (BER) is a fundamental pathway that safeguards genomic integrity by detecting and removing small base lesions arising from oxidation, alkylation, deamination or spontaneous base ...
Cancer treatments like radiation and chemotherapy work by doing one main thing: shredding the DNA of cancer cells so they can no longer multiply.
A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. A new study adds to an emerging, radically new picture of how bacterial ...
The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...
A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA. Published online May 16 in the journal Cell, the report describes the ...