Talk about a nightmare condition. Struggling to sleep is a common issue, with nearly 1 in 5 adults tossing and turning all night long. But trouble sleeping may be the least of your worries if you’re ...

Context: Fatal familial insomnia (FFI) is a genetically transmitted neurodegenerative prion disease that incurs great suffering and has neither a treatment nor cure. The clinical literature is devoid ...

The first sign of my father’s decline came at his lunchtime basketball game. At 66-years-old, he’d always been healthy and active. Then he tripped during a game. A few weeks later, he forgot where to ...

Can’t sleep? It could be worse, you could be dead. And sometimes, not being able to sleep could kill you. That’s what happens in cases of fatal familial insomnia. FFI is a degenerative brain disorder ...

Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of genetic ...

Disclosure: Joyce Schenkein, PhD, has disclosed no relevant financial relationships. Disclosure: Pasquale Montagna, MD, has disclosed no relevant financial relationships.