Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able to fill such disparate niches because molecular machinery can cut out and ...

Alternative splicing is a genetic process where different segments of genes are removed, and the remaining pieces are joined together during transcription to messenger RNA (mRNA). This mechanism ...

Researchers have harnessed a bacterial immune defense system, known as CRISPR, to efficiently and precisely control the process of RNA splicing. The technology opens the door to new applications, ...

On some level, biology is all about regulation, regulation, regulation. One way that our cells regulate their genes is through a process called alternative splicing, which entails the selective ...

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...

The predicted protein structure of FNBP1, one of the potential cancer-driving genes. The study predicts that inclusion of the exon (in yellow) helps cancer cells grow and spread. Researchers at the ...

Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialized molecular process known as "minor splicing." ...

Researchers uncovered 214,516 unique isoforms in the developing neocortex -- over 70% of which have not been previously studied. A team led by researchers at UCLA and the University of Pennsylvania ...