An AI model that screens ionizable lipids by 3D conformation identified a candidate 14.8 times more efficient than current ...

Messenger RNA (mRNA) therapeutics have moved from a promising idea to clinical reality, accelerating vaccine development and ...

The most common side effects of mRNA vaccines like the COVID-19 shot are well known: soreness, mild fever, and general ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Scientists who work with lipid nanoparticles (LNPs) say they have developed a new type of material capable of reaching the lungs and the eyes. They call their study “Thiophene-based lipids for mRNA ...

Researchers at The Hospital for Sick Children (SickKids) have uncovered how the bacteria that causes tuberculosis fuels ...

Bethesda, MD – In response to the growing number of lipids expected to be discovered through lipidomics and in anticipation of the massive amounts of data that will be generated by the lipid community ...

KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, has discovered how cancer cells can ...

Glycosylphosphatidylinositol (GPI) anchoring is an important post-translational modification, which tethers non-transmembrane proteins to the outer leaflet of the plasma membrane (PM). It participates ...