Lymph nodes are key control centers in the immune system and play an important role in defending the body against infections ...

In aggressive lymphomas, inflammatory messengers reprogram the "conductors" of the immune system, causing lymph nodes ...

However, researchers now suggest that lymph nodes are not essential in the mouse in marshalling T-cells (a main immune foot soldier) to respond to a breach of the skin barrier. This result is both ...

These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

The frequent spread of certain cancers to lymph nodes often necessitates surgery or radiation therapy that damages the lymphatic system. The new study demonstrate for the first time that growth factor ...

A recent paper in Nature Biomedical Engineering, by Dr. David J. Mooney demonstrated how a new vaccine can enhance and maintain lymph node function to boost immunity against cancer in mice. Mooney, a ...

Transplanting donor cells into lymph nodes regenerates liver, pancreas and thymus function in mice. Lymph nodes have long been known as 'secondary' lymphoid organs where mature lymphocytes interact ...

Researchers revealed in a study that offers significant insights into the causes of human lymph node function decline with ageing and the effects on immune system performance. The findings of the ...

In most patients with melanoma who develop metastases, the regional lymph nodes are the first organs to be affected. The techniques of lymphatic mapping and sentinel-node biopsy (LM/SNB) can identify ...

If we imagine our immune system to be a police force for our bodies, then previous work has suggested that the Lymph nodes would be the best candidate structures within the body to act as police ...