The complement system may be activated by three pathways, the classical (when the C1 complex is activated), the alternative (when spontaneously formed C3b is deposited on a non-inhibitory surface) and ...
The inflammatory bowel diseases (IBD), Crohn’s disease (CD), and ulcerative colitis (UC), are complex multifactorial traits involving both environmental and genetic factors. Mannan-binding lectin (MBL ...
Fuzuloparib Maintenance Therapy in Patients With Platinum-Sensitive, Recurrent Ovarian Carcinoma (FZOCUS-2): A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Trial In this single ...
Cardiovascular disease is an important complication in patients with systemic lupus erythematosus (SLE). Variant alleles of the mannose-binding lectin gene are associated with SLE as well as with ...
Figure 1: Mannose-binding lectin (blue strands) can bind to sites on the SARS-Cov-2 spike protein on the cell membrane. One of the most striking features of the SARS-CoV-2 pandemic is that across all ...
In a recently published article in the journal Cells, scientists have provided a detailed description of the utility of mannose-specific lectins in preventing coronavirus infections. They have ...
A man who had been born in 1967 was essentially healthy until 1980, when he received a diagnosis of ulcerative colitis. The condition was successfully treated with topical prednisolone. In 1996 ...
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