In the choreography of meiosis—the process responsible for sex cell division in all eukaryotic life—the pairing of homologous chromosomes (homologs) is essential. Errors in this process can lead to an ...

A research collaboration based in Kumamoto University (Japan) has clarified how homologous chromosome pairing--a process necessary for sperm and egg formation where paternally- and maternally-derived ...

For sexual reproduction to yield healthy offspring, newly generated oocytes—immature egg cells—must receive the correct amount of DNA after cell division. This process of segregating chromosomes ...

During sexual reproduction, haploid gametes (i.e. eggs and sperm) are generated from diploid precursors through the specialized cell division of meiosis. Meiosis reduces ploidy by following one round ...

During prophase I of meiosis, chromosomes become organized as loop arrays around the proteinaceous chromosome axis. As homologous chromosomes physically pair and recombine, the chromosome axis is ...

Figure 1: Image showing that protein-based artificial kinetochores (magenta) can interact with spindle microtubules (green) in a similar manner to chromosomes (cyan ...

DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and ...

A team of scientists has discovered how the X and Y chromosomes find one another, break, and recombine during meiosis even though they have little in common. As chromosomes go, X and Y make an ...

High-resolution images show excess DNA double-strand breaks formed in DEHP-exposed nuclei destined to become egg cells. Mid-pachytene nuclei (chromosomes in blue) in germlines dissected from control ...

Researchers have clarified how homologous chromosome pairing -- a process necessary for sperm and egg formation where paternally- and maternally-derived chromosomes match and exchange genetic ...