Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and releasing ...

Microglia play a central role in the neuroinflammation associated with Alzheimer’s disease (AD). These cells act as the brain’s immune system and respond to damage signals such as amyloid accumulation ...

Findings reveal that microglia may serve as a potential therapeutic target for the treatment of hyponatremia-related neurological dysfunctions and osmotic demyelination syndrome (ODS) Low serum sodium ...

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life. Scientists have reasoned that replacing the ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed ...

A key Alzheimer’s drug has finally revealed its secret. Researchers discovered that lecanemab works by activating the brain’s immune cells—but only through a specific part of the antibody called the ...

A team from the Spanish National Cancer Research Centre (CNIO) has discovered a novel way in which tumor cells alter the ...

Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize ...

Cellular aging is a central feature of neurodegenerative diseases, and microglia, the brain’s resident immune cells, are especially susceptible. Alas, whether this reflects intrinsic wear and tear or ...