Using powerful new visualization technologies, researchers have captured the first 3-D images of the structure of a key muscle receptor, providing new insights on how muscles develop across the animal ...

The flow of water within a muscle fiber may dictate how quickly muscle can contract, according to a new study. The flow of water within a muscle fiber may dictate how quickly muscle can contract, ...

Penile erection is a complex and regulated process that involves the dilation of penile blood vessels, the relaxation of smooth muscle, increased intracavernosal blood flow, and veno-occlusive ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Ataxia-telangiectasia (A-T) is a rare neurodegenerative disorder caused by the deficiency of the serine/threonine kinase ataxia telangiectasia mutated (ATM) protein, whose loss of function leads to ...

Because RyR1 is also expressed in neurons, immune cells, and vascular smooth muscle, the E3896A model offers a unique tool to examine CICR's broader physiological roles. By combining gene engineering, ...