While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Cancer’s strongest gene switches push DNA into damaging overdrive, creating repeated breaks and repairs that may fuel tumor ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations in mitochondrial DNA using a genetic tool known as a base editor. The ...

Even back then, scientists were puzzled. Many prediction models suggested this fish shouldn’t survive beyond roughly 10,000 ...

The Iñupiat people of Alaska have long said that bowhead whales live two human lifetimes. That oral knowledge turned out to be conservative.

Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations This was a phase II multicenter trial in which refractory solid ...

A protein tied to ALS and dementia may have a much bigger role in disease than scientists realized. Researchers found that TDP43 controls a key DNA repair process, but when the protein becomes ...

Learn how the Amazon molly, an all-female fish that reproduces asexually, uses gene conversion to maintain healthy DNA and ...

A team of cancer genomics scientists from The University of Manchester and The Institute of Cancer Research, London, ...

QUICK FIX: From left, Frederick Alt and Guillermo Taccioli and their colleagues identified DNA-dependent kinase as a key enzyme involved in DNA repair. The way that DNA repairs itself recently has ...