The authors set out to answer a simple question. Do all chromosomes have the same chance of being mis-segregated during cell division? To address this, Klaasen and colleagues turned to several types ...

Using computer simulations, chemists have discovered how nuclear bodies called nucleoli interact with chromosomes in the nucleus, and how those interactions help the nucleoli exist as stable droplets ...

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell. This knowledge is crucial for analyzing how DNA structure influences gene ...

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion. This allows specific regions to come into contact and thereby activate a gene. A ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Michael Rout has spent decades studying the molecular machinery that controls all traffic in and out of the cell’s nucleus.

In about one out of every 800 people, two chromosomes fuse together to form an unusual bond. These are known as Robertsonian chromosomes. It's a mystery that has long stumped scientists. Now, ...

M. Jagannathan et al., “A conserved function for pericentromeric satellite DNA,” eLife, 7:e34122, 2018. Between cell divisions, pericentromeric DNA—noncoding, repetitive satellite DNA abundant around ...

Whether at the start of a sinus infection or a fresh open wound, neutrophils are the first line of defense in an immune attack. 1 In order to rush to the scene to kill infectious microbes, they have a ...