Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is hampered by perseverant drug cravings that may persist for months after cessation of drug use. Drug cravings ...

A major obstacle in oxycodone addiction treatment is relapse during abstinence. In rats, oxycodone seeking intensifies during abstinence, and orbitofrontal cortex (OFC) is critical for this incubation ...

In a recent study published in the journal JCPP Advances, a group of researchers investigated whether early negative life events (NLEs) predict depressive symptoms in young adulthood through ...

The orbitofrontal cortex (OFC), a subsection of the brain's frontal lobe, is known to play a part in value-based decision-making, the process of mentally weighing the outcome of different decisions ...