Retrospective validation of a novel multimodal AI prognostic tool integrating digital pathology and clinical data against real world data and Oncotype DX in a Swiss breast cancer cohort. This is an ...

RNA, historically regarded merely as a messenger for genetic information, is now recognized as a pivotal molecule in the origin of life, as proposed by the RNA World Hypothesis 1. Like proteins, many ...

Eighteen groups involved in 3D prediction of RNA participated in this round. See Methods for descriptions of the prediction tools used by each group. Each modeling group may submit sets of results ...

Announcing a new publication for Acta Materia Medica journal. Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational ...

A novel non-invasive machine learning model for predicting tertiary lymphoid structures and treatment response to neoadjuvant therapy in triple-negative breast cancer: A multicenter retrospective ...

The intrinsically disordered proteins (IDPs) do not attain a stable secondary or tertiary structure and rapidly change their conformation, making structure prediction particularly challenging. These ...