Protein hydrophobicity is a fundamental driver of protein folding dynamics, underpinning the formation of a central hydrophobic core that stabilises the three-dimensional structure amid an aqueous ...

High-pressure nuclear magnetic resonance (NMR) spectroscopy has emerged as a critical technique for investigating the structural dynamics of proteins under extreme conditions. By subjecting biological ...

The team, from biopharmaceutical company Regeneron, hopes their work will help researchers better understand protein-protein interactions during preclinical development of a drug. “Essentially, we ...

The cell cytoskeleton is modulated by motor proteins, known as dyneins, that generate force and movement on microtubules to control a wealth of biological processes, including motility, cell division, ...

A novel protein cage system can control and visualize orientational changes in aromatic side chains upon ligand binding. By inducing coordinated molecular changes, this approach enables precise ...

Explore advances in protein imaging techniques and spatial proteomics. Learn how modern imaging tools reveal protein dynamics and organization in cells.

EPFL researchers have developed a light-based method that can produce proteins that switch states, respond to signals, and even compute, using light and the cell cycle.