In chemistry, breaking a mirror isn’t always a harbinger of bad luck. Using a trio of catalysts and some blue light, researchers have transformed a racemic mixture of mirror-image molecules into a ...
The latest short science news items from C&EN. In order for the catalyst to be stereoselective, its ligand has to be able to distinguish between the different alkyl substituents. Fu’s hunch about how ...
A combined team of researchers from Princeton University and Yale University has developed a multicatalytic technique to enrich racemic mixtures directly to a single enantiomer in a single step. In ...
ANDOVER, Mass.--(BUSINESS WIRE)--DeuteRx, LLC, is a research and development-focused biotechnology company dedicated to improving racemic small molecule marketed drugs and drug candidates intended for ...
Deracemization is a powerful method by which a racemic mixture can be transformed into an excess of one enantiomer with the aid of chiral auxiliaries, but has been applied only to small chiral ...
From 2001 to 2011, the US Food and Drug Administration approved 9 single-enantiomer drugs with racemic precursors. None showed pre-approval evidence of improved efficacy over the racemic precursor. We ...
New biocatalytic and chemocatalytic routes to chiral intermediates and developments in simulated-moving-bed and supercritical-fluid chromatography for resolving racemic mixtures. The prevalence of ...
Acute bronchiolitis in infants frequently results in hospitalization, but there is no established consensus on inhalation therapy — either the type of medication or the frequency of administration — ...
THE separation of racemic mixtures of optical isomers is still limited, with rare exceptions, to the methods of Pasteur. For this reason the resolution of substances which seem identical in the ...
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