A SARS-CoV-2 subvariant called BA.3.2, carrying a significant genomic deletion and mutations linked to immune evasion, has ...

Men have higher morbidity and mortality from COVID-19 than women, possibly due to androgen receptor-regulated viral entry protein expression. This led to a clinical trial of androgen deprivation ...

The JN.1 subvariant of SARS-CoV-2 emerged in late 2023 and rapidly became dominant globally. In the past 6 months, JN.1 has continued to evolve, giving rise to multiple sublineages with unique spike ...

Since the start of the COVID-19 pandemic, there has been controversy surrounding the origins of SARS-CoV-2. New research from the University of California, San Diego (UCSD), School of Medicine ...

Harnessing AI agents and human expertise, researchers accelerate the design of innovative nanobodies to combat evolving SARS-CoV-2 variants. Study: The Virtual Lab: AI Agents Design New SARS-CoV-2 ...

The question of the origin of SARS-CoV-2 continues to occupy scientists, the media, and the public intensely even 5 years after the onset of the COVID-19 pandemic. Where the virus came from, when and ...

Researchers have discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity. This significantly ...

Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these ...

Two of the closest known relatives to SARS-CoV-2 -- a pair of bat coronaviruses discovered by researchers in Laos -- may transmit poorly in people despite being genetically similar to the ...

We conducted a phase 2–3 double-blind trial to assess the efficacy and safety of nirmatrelvir–ritonavir in asymptomatic, rapid antigen test–negative adults who had been exposed to a household contact ...