Researchers report a drug discovery strategy using tailor-made cyclic peptides to target β-arrestins, key regulators of ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...

Signal transduction is the fundamental process by which cells convert external cues into tailored intracellular responses. Through a cascade of molecular events—beginning at the cell membrane with the ...

Two-component signal transduction systems (TCS) are fundamental to the ability of bacteria and certain lower eukaryotes to sense and respond to environmental changes. Typically composed of a sensor ...

A research team under the direction of the Medical University of Vienna has identified a potential new method for drug development in a recently published review.

Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

That’s gene editing. On paper, it is merely the rearrangement of letters. However, the road to editing genes in hopes of a therapeutic benefit is difficult to travel. Additionally, researchers want ...

Edited by: James Kling P.A. Hoodless, T. Haerry, S. Abdollah, M. Stapleton, M.B. O'Connor, L. Attisano, J.L. Wrana, "MADR1, a MAD-related protein that functions in ...