Bioengineers at the University of California, San Diego have proven that when it comes to guiding stem cells into a specific cell type, the stiffness of the extracellular matrix used to culture them ...

A new study, led by Prof. Liu from the department of pharmacy, University of Electronic Science and Technology of China, discovered that the extracellular cell matrix (ECM) could induce the drug ...

Newswise — Intervertebral disc degeneration (IVDD) is a leading cause of chronic back pain and disability, impacting millions of people worldwide. Characterized by the breakdown of the disc’s ...

Tumors have a unique niche system that plays an important role in their occurrence and development. At present, there is increasing interest in the biomechanical properties of niches. The increased ...

A recent study led by Stanford School of Medicine researchers suggests that extracellular matrix effects on the phenotypic modulation of endothelial cells play a critical role in atherosclerosis, a ...

A new review maps how mechanically adaptive hydrogels that dynamically tune their stiffness, combined with finite element ...

Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...