When neuroscientists analyzed the exact properties of nerve connections in the brain, they made a startling observation: At a key connection, or synapse, messages are sent against the usual stream of ...

How do people think, feel, remember, and move? These processes rely on synaptic transmission, where chemical signals are passed between nerve cells using molecular structures called vesicles.

The regulation of neuronal excitability and the maintenance of an appropriate balance between excitation and inhibition are central to brain function. Inhibitory synaptic transmission, predominantly ...

Physiological functioning and homeostasis of the brain rely on finely tuned synaptic transmission, which involves nanoscale alignment between presynaptic neurotransmitter-release machinery and ...

BIN1, one of the strongest genetic risk factors for late-onset Alzheimer’s disease, encodes a protein that dabbles in many cellular functions, taking a hand in Aβ production, tau propagation, and ...

Tau proteins are involved in more than twenty neurodegenerative diseases, including various forms of dementia. These proteins clump together in patients’ brains to form neuronal tangles: protein ...

Synaptic transmission is the biological process by which a neuron communicates with a target cell across a synapse. Chemical synaptic transmission involves the release of a neurotransmitter from the ...

This study is led by Prof. Jun Li (Peking University Sixth hospital), Prof. Dai Zhang (Peking University Sixth hospital), Dr. Yuanlin Ma (Peking University Sixth hospital; The First Affiliated ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

This is a preview. Log in through your library . Abstract Hyperpolarization-activated nonselective cation channels (Ih channels) play an important role in the control of membrane excitability and ...

Our concepts of how the two and a half pounds of flabby flesh between our ears accomplish learning date to Ivan Pavlov’s classic experiments, where he found that dogs could learn to salivate at the ...