The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

The 49ers host the Rams on Thursday Night Football. They’ve been losing running backs left and right, and now we’re awaiting ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

The San Francisco 49ers’ Week 15 injury report inspired a little bit of optimism on the health front as they enter a virtual ...

San Francisco 49ers rookie running back Isaac Guerendo is dealing with a foot injury and is listed as questionable for Week 15 against the Los Angeles Rams on T ...

San Francisco 49ers running back Isaac Guerendo has a foot sprain, per head coach Kyle Shanahan. 49ers HC Kyle Shanahan said ...

Niners running back Isaac Guerendo, who is listed as questionable with a sprained foot, insists he "feels good" for ...

The 49ers are playing on "Thursday Night Football" against the Rams. Will running back Isaac Guerendo be ready to play after ...

After Christian McCaffrey (knee) and Jordan Mason (ankle) were moved to injured reserve last week, Guerendo stepped in as the 49ers' starting running back in this past Sunday's 38-13 win over the ...

Three of last week’s top pickups — Isaac Guerendo (26.8 points), Adam Thielen (19.2) and Juwan Johnson (15) — won matchups in ...