If your keyboard or mouse not working in Safe Mode, the problem may be with the respective device drivers. Use these fixes to resolve the issue.

When you open your computer in Safe Mode, you will see an option that says Enable Safe Mode with Networking.

1. Start your computer in safe mode: Goto: Start – Run – msconfig – OK. The System Configuration Utility box opens up. Click on the BOOT.INI tab and check /SAFEBOOT – Minimal from Boot Options. Click ...