A phase 1/2 trial of a novel viral vector gene therapy in adults with type 1 diabetes is scheduled to begin this year.

Researchers said their discovery of nine 'core' genes central to the development of type 1 diabetes could unlock new immune system pathways for targeting by immunotherapies. A team from the University ...

Missing genes and sequencing read registration in single-cell RNA-seq experiments. Credit: Nature Methods (2023). DOI: 10.1038/s41592-023-02003-w In 2018, researchers in the Caltech laboratory of Yuki ...

An international study co-led by researchers from the University of Massachusetts Amherst and Helmholtz Munich in Germany has uncovered hundreds of genes and proteins likely to play a causal role in ...

Advances in human genetics have enabled the investigation of the genetic architecture underlying numerous complex traits. Many publicly available databases establish a binary relationship between ...

Nature and nurture both determine how likely you are to develop a particular disease. Hiroshi Watanabe/DigitalVision via Getty Images Sitting in my doctor’s examination room, I was surprised when she ...

Some people have a greater genetic risk than others of developing type 2 diabetes. Now, more of these at-risk people are ...

Children with hereditary deafness regained their hearing thanks to a type of gene therapy, a new study published on Wednesday found. In a clinical trial, co-led by investigators from Mass Eye and Ear, ...

The research team discovered that this type of regulation, which appears to influence the expression of about half of all human genes, is found throughout the animal kingdom, as well as in plants. The ...

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St ...