For over 350 years, quinine and other extracts from the cinchona tree (Cinchona spp.) were the only effective medicines ...

Enzymes that play a crucial role in the production of the malaria drug quinine and other important cinchona alkaloids have ...

Cinchona alkaloids have a long and storied history in chemistry. Derived from Cinchona plants, members of the molecular family include the chiral catalyst cinchonidine and quinine, an early ...

Characteristic features of plants, such as their active ingredients or flower color, may have developed through very ...

Researchers mapped the full biosynthesis of quinine in cinchona trees, identifying key enzymes and intermediates. The ...

A team of scientists has identified an enzyme called PurF as a new drug target for tuberculosis, offering a fresh line of ...

Newly discovered enzymes found in the cinchona tree play a crucial role in the production of the malaria drug quinine and other important alkaloids. This opens up possibilities for the ...

Researchers identify the crucial protein for controlling the biosynthesis of steroidal glycoalkaloids and saponins in plants of the genus Solanum and for the first time demonstrate the ecological role ...

The cancer drug paclitaxel has captured the imaginations of chemists for decades, in part because of its complex polycyclic core with an oxetane ring. Although scientists have synthesized the molecule ...