Long-term abuse of cocaine induces compensatory changes in numerous genes associated with brain function. These compensatory changes lead to the appearance of the classic series of withdrawal symptoms ...
This study is led by Prof. Chaoran Ren (Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan university), Prof. Tifei Yuan (Shanghai Mental Health Center, Shanghai Jiaotong University School ...
In the realm of drug use, cocaine use disorder (CUD) remains a significant challenge without approved pharmacotherapies. Behaviors like addiction are driven by lasting molecular alterations in brain ...
A new study has provided the first evidence of a link between the gut microbiome and cocaine use and the cravings that follow withdrawal. The findings open the door to potential treatments for drug ...
Why do so many people relapse after quitting cocaine? A new study from The Hebrew University reveals that a specific "anti-reward" brain circuit becomes hyperactive during withdrawal-driving ...
Study: Molecular and circuit determinants in the globus pallidus mediating control of cocaine-induced behavioral plasticity. Image Credit: Alex Mit / Shutterstock.com Ventral tegmental area dopamine ...
(Boston)—Substance use disorder is a major concern with few therapeutic options. In 2019, close to 20.4 million people were diagnosed with substance use disorder, and nearly 71,000 people died of an ...
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