The San Francisco 49ers improved to 8-4 on Monday Night Football, but reaching the postseason will still prove to be tough.

ESPN’s Dan Orlovsky says he’d be “shocked” if the NFC Super Bowl team isn’t the Rams, Seahawks or Eagles, leaving the 49ers out of his contender tier.

The NFL announced Tuesday that it suspended Carolina Panthers defensive back Tre'Von Moehrig for one game for striking San Francisco 49ers' Jauan Jennings in the groin area.

The San Francisco 49ers defense locked down the Carolina Panthers and the offense was able to overcome three first half ...

Brock Purdy's return was meant to boost the San Francisco 49ers' offense, but his second game back saw a different story.

Three first-half interceptions turned Purdy into a dink-and-dunker for the rest of the game. The 49ers need the good Purdy ...

Is it Mac Jones time in San Francisco? If you were hoping for competent quarterback play on Monday night, you were still left ...

As head coach Ben Johnson told this Chicago Bears team several weeks ago, don't ever apologize for a win in this league. It's ...

McCaffrey gains 142 yards from scrimmage (89 rushing) and scores a touchdown in a 20-9 win, his first game against his former ...

San Francisco 49ers register back-to-back wins for the first time since September to boost their play-off hopes by overcoming ...

San Francisco 49ers head coach Kyle Shanahan gives remarks following the Week 12 matchup vs. the Carolina Panthers.