Tolerance and withdrawal are not universal features of substance use disorder; hallucinogens, for example, do not create tolerance or withdrawal symptoms. Does psychological dependence exist?

Watch ‘The Substance’ on MUBI (via Prime Video) Directed by Coralie Fargeat, The Substance follows Elisabeth Sparkle (Demi Moore), an aging celebrity who turns to a mysterious miracle drug ...

A rare and dangerous substance has been discovered in eastern North Carolina for the first time. Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate, or BTMPS, is a chemical with industrial uses like a ...

When Demi Moore won best actress at the Critics Choice Awards for "The Substance," she thanked voters for recognizing a horror film, saying movies in the genre are normally "overlooked and not ...