Mechanochemical synthesis harnesses mechanical energy to drive chemical transformations under solvent‐minimised or solvent-free conditions. This approach, frequently executed by ball milling or liquid ...

The Biginelli reaction, first reported over a century ago, represents a robust three‐component condensation strategy to synthesise 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) from accessible substrates ...

New, improved formulations of frequently used organolithium reagents that improve on safety, prevent pyrophoric reactions and ...

As an engineering plastic having high transparency and impact resistance, polycarbonate (PC) is employed in eyeglass lenses, camera lenses, DVDs, automobile headlights and bulletproof glass. The ...

The synthesis of methanol from carbon dioxide can be dramatically improved by switching the catalyst support from zirconia to ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound.

With artificial intelligence, scientists can design increasingly complex small molecule structures. Automation is critical for transforming these compounds from designs on a screen into actual ...

The new reaction enables selective modification of anti-cancer drugs, rapid synthesis of medicinal compounds, and production ...

When Clay Bennett started his postdoctoral stint in 2005, he thought—“naively,” he admits—that he would spend just a couple of months preparing a few grams of an oligosaccharide before using the ...

The first time Ryan Shenvi played Wordle, when the popular word-guessing game was just taking off, he remembers thinking, “Oh, we should do this for retrosynthesis.” The La Jolla–based Scripps ...