Head coach Kyle Shanahan and defensive coordinator Nick Sorensen broke down the team's performance against the Green Bay ...

The Bills and 49ers meet on Sunday Night Football in a game with playoff implications for both teams. Here are three ...

San Francisco 49ers head coach Kyle Shanahan told reporters that star quarterback Brock Purdy will practice with the team ...

The San Francisco 49ers' 2024 season has not gone as planned. Sitting at 5-6 and in last place in the NFC West, the team is ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

San Francisco 49ers quarterback Brock Purdy suffered a shoulder injury back in Week 11 against the Seahawks and was held out ...

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

The San Francisco 49ers are reportedly hoping that quarterback Brock Purdy's shoulder injury isn't a long-term issue, but ...

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game ...

If defense wins championships, NFL quarterbacks win headlines—and a whole lot of blame when things go south. Week 12 gave us ...

San Francisco quarterback Brock Purdy took part in some light throwing on Monday after missing his first career game because ...

The Buffalo Bills' upcoming opponent, the San Francisco 49ers, provided a big injury update for their starting quarterback ...