The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, ...

An MRI exam on Monday morning revealed that San Francisco 49ers rookie running back Isaac Guerendo (ankle, knee) suffered an MCL sprain and an ankle sprain in the loss to the division-rival Arizona ...

After three straight seasons of long playoff runs, the San Francisco 49ers are packing up and heading home early for a change ...

San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL injury.

Rookie Isaac Guerendo battled injuries himself after taking the lead role in the backfield, and was carted off during the ...

The season from the abyss is finally over for the San Francisco 49ers. They suffered a blowout loss to the Arizona Cardinals, ...

Terique Owens, Trent Taylor and Tanner Mordecai lead a group of 11 players who signed reserve/future contracts with the 49ers ...

The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?

San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the ...

Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The ...

There wasn’t much to play for when the San Francisco 49ers and Arizona Cardinals suited up Sunday at State Farm Stadium. The ...