San Francisco 49ers running back Isaac Guerendo was carted off the field in the first quarter against the Arizona Cardinals.

Rookie running back Isaac Guerendo was carted off the field early in the 49ers’ season finale in Arizona against the ...

San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers’ season finale versus the Arizona ...

Experts have released new player stat projections alongside updated prop odds for Monday's Lions-49ers NFL Week 17 Monday ...

There are numerous player prop betting options on Isaac Guerendo for the 8:15 PM ET game Monday, which airs live on ABC/ESPN.

GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...

The San Francisco 49ers have had to deal with multiple running back injuries this season and another went down in Week 18 against the Arizona Cardinals. Rookie Isaac Guerendo went down on the fourth ...

While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...

The San Francisco 49ers entered Sunday's season finale against the Arizona Cardinals with a depleted roster. Quarterback Josh Dobbs took the reins in place ...

San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury ...

The 49ers lost another running back Sunday. Isaac Guerendo was carted off the field with injuries to his left knee and ankle. The team ruled out his ...

San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the ...