Isaac Guerendo, San Francisco 49ers

Latest update on Isaac Guerendo’s knee brings positive news for the 49ers ahead of the 2025 NFL season
The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be complete in time for the upcoming NFL season.
49ers RB Isaac Guerendo carted off with knee and ankle injuries
San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers ‘ season finale versus the Arizona Cardinals.
49ers RB Isaac Guerendo shares positive injury update
San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. He was
49ers running back Isaac Guerendo carted off with leg injury
Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ season finale in Arizona against the Cardinals with a leg injury.
Isaac Guerendo injury update: San Francisco 49ers RB carted off field after scary tackle
San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury after a scary tackle during the first series of the game. After Isaac Guerendo left the field,
49ers’ Isaac Guerendo Suffers Injury in Season Finale vs. Cardinals
Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.
49ers' Isaac Guerendo Says His 'ACL Is Good' After Being Carted Off with Injury
San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated:
49ers RB Isaac Guerendo 'good to go' vs. Lions
San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the Lions.
49ers' Isaac Guerendo: Has MCL, ankle sprains
Guerendo has been diagnosed with MCL and ankle sprains in his left leg following an MRI on Monday, but he didn't damage the ACL in his left knee during Sunday's loss at Arizona, Matt Barrows of The Athletic reports.
49ers rookie may have avoided major injury in loss to Cardinals
San Francisco running back Isaac Guerendo exited the 49ers' season finale versus the Arizona Cardinals just four plays into the contest. On his second carry of the afternoon, Guerendo's left leg was twisted up and he had to be carted off.
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MRI reveals 49ers RB Isaac Guerendo suffered MCL, ankle sprains
San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL ...
Standout 49ers rookie delivers positive update after scary Week 18 injury
The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?
49ers' Isaac Guerendo: Won't return Sunday
Guerendo won't return to Sunday's game at Arizona due to knee and ankle injuries. Guerendo had his left leg twisted under him on his second carry of the game, and his teammates quickly motioned to the ...