Real neurons don't actually talk to each other with electrical spikes. For that, their synapses deploy vesicles filled with transmitters. Although there is clearly a relation between the spikes a ...

Schematic representation of axonal transport vesicles (blue) carrying presynaptic proteins (SV and AZ proteins). Kinesin motor proteins (KIF1A) attach these vesicles and carry them along the axons to ...

They used synapses from the fruit fly drosophila, which compares remarkably closely to synapses in humans. The results showed that two variations of a protein called Unc13 work separately to regulate ...

Researchers from The University of Texas at Dallas’ Center for Advanced Pain Studies (TX, USA) and their colleagues have made a fundamental discovery about a key mechanism that enables nervous system ...

Synapse labeling strategies involve marking synaptic contact sites with different fluorescent proteins in the pre- and postsynaptic compartments. The interface between these contacts is also labeled, ...