Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor ...

A newly identified protein pair may drive brain cell death in Alzheimer’s, offering a clearer explanation of how the disease progresses.

Can we prevent brain hemorrhages without surgery? New research identifies TIE2 as a key driver of cerebral cavernous malformations (CCMs). Discover how the drug rebastinib could provide a safer, ...

Intracellular peptides, generated predominantly via the ubiquitin–proteasome system, have emerged as critical modulators of cell signalling. These peptides play multifaceted roles, ranging from ...

UT Southwestern Medical Center researchers have identified how the quintessential immune protein known as stimulator of ...

The data shows that inhibiting TIE2 with rebastinib could prevent new abnormalities from forming in the brain with fewer side effects.

Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, largely due to metastasis and ...

Gut bacteria aren’t just passive passengers—they can actively send proteins straight into our cells. Using microscopic injection systems, even harmless microbes can influence immune responses and ...

Peptide science has expanded rapidly in recent decades, revealing molecules with intriguing signaling roles that may influence diverse regenerative and organizational processes within an organism.

New study traces how a protein essential for hearing evolved from an ancient ion channel into today’s exquisitely sensitive ...