San Francisco 49ers running back Isaac Guerendo is expected to play in Thursday's pivotal game against the LA Rams, according ...

The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

Starter Christian McCaffrey (knee) is amid his second IR stint, and his backup, Jordan Mason, is also on IR with a high-ankle ...

If the San Francisco 49ers want to defend their NFC West title, they must defeat the Los Angeles Rams in Week 15. However, the team enters Thursday Night Footba ...

Is Isaac Guerendo playing on "Thursday Night Football" or is he out? Is Isaac Guerendo injured or healthy for Week 15 TNF?

ESPN’s Adam Schefter reported that San Francisco 49ers running back Isaac Guerendo will try to play tonight against the Los ...

The 49ers host the Rams on Thursday Night Football. They’ve been losing running backs left and right, and now we’re awaiting ...

Fantasy football analyst Scott Pianowski highlights the best (and worst) playoff schedules for receivers around the league.

Rams vs. 49ers at 8:20 p.m. ET/5:20 p.m. PT on Amazon Prime Video. This is it, my fellow fantasy football heads — the first ...