The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” ...

Rookie running back Isaac Guerendo is expected to play through a foot sprain tonight against the Los Angeles Rams. Guerendo ...

The San Francisco 49ers running back spot has been a position of focus for fantasy football players throughout the season, ...

The top injuries to monitor. Plus, Jake Ciely's player rankings, weather reports and more fantasy and betting insights.

Isaac Guerendo was initially uncertain for Thursday night, but the rookie looks like he might give it a go. Here's the latest ...

The 49ers won’t be down to their 4th-string running back tonight against the Rams as Isaac Guerendo is expected to play ...

Isaac Guerendo became the team's starter last week and the rookie scored two touchdowns against the Bears, but his day ended ...

The Los Angeles Rams will take on the San Francisco 49ers in Week 15 of the NFL season on Thursday. This prediction is based ...

The 49ers host the Rams on Thursday Night Football. They’ve been losing running backs left and right, and now we’re awaiting ...

The San Francisco 49ers’ Week 15 injury report inspired a little bit of optimism on the health front as they enter a virtual ...

Now, it looks as though the 49ers may be down yet another running back, as Isaac Guerendo was forced out of Sunday’s game ...

San Francisco 49ers rookie running back Isaac Guerendo sustained a foot injury and is questionable to return in Sunday's ...