At least 21 people have died in monsoon rain-related incidents in Pakistan, authorities said, pushing the nationwide death toll over the last week above 400 as floods and landslides continue to devastate large parts of the country.

Pakistan ordered businesses, schools and public offices in Karachi to shut on Wednesday after torrential monsoon rain left at least 10 people dead in the densely populated port city, with more heavy downpours predicted.

More than 20 people were killed on Wednesday in a torrential spell of monsoon rain in Pakistan, where downpours have swept away entire villages over the last week, leaving more